There are 7 airlines that fly directly from Madrid to Rome: Wizz Air, Ryanair, Alitalia, Air Europa, Iberia, Vueling, LC Peru if you are departing from Madrid. Most airlines that have direct connections are departing from Madrid Barajas International Airport. Most airlines arrive to Leonardo da Vinci-Fiumicino Airport. Most flights depart on Tuesday, Saturday.
Airlines that have direct flights from Madrid to Rome
No direct flights to Rome